演讲嘉宾简介
阮一骏 教授
美国杰克逊实验室
个人网页：http://research.jax.org/faculty/yijun-ruan.html
研究方向:
通过DNA测序的方法在基因组和转录组水平研究功能性DNA元件的结合和变化。
近期发表论文:1. Xu Q, Chen LL, Ruan X, Chen D, Zhu A, Chen C, Bertrand D, Jiao WB, Hao BH, Lyon MP, Chen J, Gao S, Xing F, Lan H, Chang JW, Ge X, Lei Y, Hu Q, Miao Y, Wang L, Xiao S, Biswas MK, Zeng W, Guo F, Cao H, Yang X, Xu XW, Cheng YJ, Xu J, Liu JH, Luo OJ, Tang Z, Guo WW, Kuang H, Zhang HY, Roose ML, Nagarajan N, Deng XX, Ruan Y* (2012) The draft genome of sweet orange (Citrus sinensis). Nature Genetics 2012 Nov 25. doi: 10.1038/ng.2472. [Epub ahead of print]
2. Sandhu KS, Li G, Poh HM, Quek YL, Sia YY, Peh SQ, Mulawadi FH, Lim J, Sikic M, Menghi F, Thalamuthu A, Sung WK, Ruan X, Fullwood MJ, Liu E, Csermely P, Ruan Y* (2012) Large-Scale Functional Organization of Long-Range Chromatin Interaction Networks. Cell Reports 2012 Oct 24. pii: S2211-1247(12)00326-9. doi: 10.1016/j.celrep.2012.09.022. [Epub ahead of print]
3. Ng KP, Hillmer AM, Chuah CT, Juan WC, Ko TK, Teo AS, Ariyaratne PN, Takahashi N, Sawada K, Fei Y, Soh S, Lee WH, Huang JW, Allen JC Jr, Woo XY, Nagarajan N, Kumar V, Thalamuthu A, Poh WT, Ang AL, Mya HT, How GF, Yang LY, Koh LP, Chowbay B, Chang CT, Nadarajan VS, Chng WJ, Than H, Lim LC, Goh YT, Zhang S, Poh D, Tan P, Seet JE, Ang MK, Chau NM, Ng QS, Tan DS, Soda M, Isobe K, Nöthen MM, Wong TY, Shahab A, Ruan X, Cacheux-Rataboul V, Sung WK, Tan EH, Yatabe Y, Mano H, Soo RA, Chin TM, Lim WT, Ruan Y*, Ong ST*. (2012) A common BCL2L11 deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer. Nature Medicine 18(4): 521-528
4. Li G, Ruan X, Auerbach RK, Sandhu KS, Zheng M, Wang P, Poh HM, Goh Y, Lim J, Zhang J, Sim HS, Peh SQ, Mulawadi FH, Ong CT, Orlov YL, Hong S, Zhang Z, Landt S, Raha D, Euskirchen G, Wei C-L, Ge W, Wang H, Davis C, Fisher K, Mortazavi A, Gerstein M, Gingeras T, Wold B, Sun Y, Fullwood MJ, Cheung E, Liu E, Sung W-K, Snyder M, Ruan Y* (2012) Extensive Promoter-centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation. Cell 148, 84-98
5. Lusy Handoko, Han Xu, Guoliang Li, Chew Yee Ngan, Elaine Chew, Charlie Wah Heng Lee, Chaopeng Ye, Eleanor Wong, Yubo Zhang, Fabianus Mulawadi, Jianpeng Sheng, Thompson Poh, Chee Seng Chan, Galih Kunarso, Atif Shahab, Guillaume Bourque, Valere Cacheux-Rataboul, Wing-Kin Sung, Yijun Ruan*, Chia-Lin Wei* (2011) Functional Genome Architecture Revealed by CTCF-Associated Chromatin Interactome in Pluripotent Cells. Nature Genetics 43: 630–638 (June 19, 2011)