高绍荣 教授

同济大学生命科学与技术学院院长





研究方向:

1.早期胚胎发育尤其是细胞全能性建立与第一次细胞命运决定的表观遗传调控机制; 
2.利用体细胞核移植与诱导多能干细胞技术研究体细胞重编程的分子机制;
3. 利用病人诱导多能干细胞进行疾病发生机制及干细胞转化医学研究。

近期发表论文:

1. Liu X, Wang C, Liu W, Li J, Li C, Kou X, Chen J, Zhao Y, Gao H, Wang H, Zhang Y, Gao Y, Gao S. (2016) Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos. Nature 537(7621):558-562. (Previewed by Nature)
2. Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S, Wang X. (2016) LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 7:10481. (Co-correspondence)
3. Yang Y, Zhang X, Yi L, Hou Z, Chen J, Kou X, Zhao Y, Wang H, Sun XF, Jiang C, Wang Y, Gao S. (2016) Naïve Induced Pluripotent Stem Cells Generated From β-Thalassemia Fibroblasts Allow Efficient Gene Correction With CRISPR/Cas9. Stem Cells Transl Med. 5(1):8-19.
4. Xu Q, Wang F, Xiang Y, Zhang X, Zhao ZA, Gao Z, Liu W, Lu X, Liu Y, Yu XJ, Wang H, Huang J, Yi Z, Gao S, Li L. (2015) Maternal BCAS2 protects genomic integrity in mouse early embryonic development. Development. 142(22):3943-53. (Co-correspondence)
5. Yuan W, Wu T, Fu H, Dai C, Wu H, Liu N, Li X, Xu M, Zhang Z, Niu T, Han Z, Chai J, Zhou XJ, Gao S, Zhu B. (2012) Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science 337(6097):971-5. (Co-correspondence, Previewed by Science)