张亮然 教授

山东大学生命科学学院





研究方向:

1. 减数分裂同源重 组的分子机制;2. 染色体不稳定性的分子机制;3. 同源重组技术的应用。

近期发表论文:


1. Shunxin Wang, Denise Zickler, Nancy Kleckner*, Liangran Zhang* (2015) Meiotic crossover patterns: obligatory crossover, interference and homeostasis in a single process. Cell Cycle 14:305-314.
2. Liangran Zhang, Eric Espagne, Arnaud De Muyt, Denise Zickler, Nancy Kleckner (2014) Interference-mediated synaptonemal complex formation with embedded crossover-designation. Proc Natl Acad Sci USA 111(47): E5059-68.
3. Liangran Zhang, Shunxin Wang, Shen Yin, Soogil Hong, Keun P. Kim, Nancy Kleckner (2014) Topoisomerase II mediates meiotic crossover interference. Nature 511: 551–556.
4. Arnaud De Muyt*, Liangran Zhang*, Tristan Piolot, Nancy Kleckner, Eric Espagne and Denise Zickler (2014) E3 ligase Hei10: a multi-faceted structure-based signaling molecule with roles within and beyond meiosis. Genes Dev, 28: 1111-1123. (*contributed equally)
5. Liangran Zhang, Zhangyi Liang, John Hutchinson and Nancy Kleckner (2014) Crossover patterning by the Beam-Film model: analysis and implications. PLoS Genetics, 10: e1004042